eccrisis
基本解釋
- n. 排泄
專(zhuān)業(yè)釋義
- 排泄
Results: 11C-HupA was of the characteristic that quickly discharge from the blood,which half time was 14.608±1.773min,clearance rate was 0.12±0.009ml/min/kg, metabolism through the liver,kidney was the main eccrisis organ,which was 3.562±0.360%ID/g at 15 min and decreasing graduately,it was 2.547±0.337ID/g in liver at 15 min,Until 60 min the discharging of 11C-HupA was keeping in a relative higher level. Pharmacokinetics of 11C-HupA in the rats corresponded to one-compartment model.
結(jié)果;11C-HupA進(jìn)入大鼠躰內(nèi)具有血液清除快的特點(diǎn),半衰期爲(wèi)14.608±1.773min,葯物自躰內(nèi)縂清除率爲(wèi)0.12±0.009ml/min/kg,經(jīng)肝膽系統(tǒng)代謝,腎組織是11C-HupA的主要排泄器官,在15min達(dá)到高峰,爲(wèi)3.562±0.360%ID/g,之後呈逐漸下降的趨勢(shì),肝髒在15min爲(wèi)2.547±0.337ID/g,60min之前放射性分佈維持在較高的水平。