osteoclast precursor
基本解釋
- 破骨細胞前體
專業(yè)釋義
- 破骨細胞前體細胞
RNAKL induce osteoclast differentiation and function by binding to its receptor RANK (receptor activator of NF- κ B) on the osteoclast precursor and mature osteoclast.
RANKL與破骨細胞表面的RANK(receptoractivator of NF-κB,核激活因子受體)結合后,刺激破骨細胞前體細胞向成熟破骨細胞分化,也刺激了成熟破骨細胞發(fā)揮骨吸收功能。