iron homeostasis

基本解釋

AIM To explore whether there is relationship between iron homeostasis disorder and neurodegeneration induced by aluminum(Al) overload.
目的探討鋁致神經(jīng)元退行性變是否與腦鐵代謝失衡有關(guān)。
CONCLUSION Al overload may interfere with brain iron homeostasis, which may be responsible for neurodegeneration induced by Al toxicity.
結(jié)論鋁過負(fù)荷致神經(jīng)元退變可能與其干擾腦鐵代謝有關(guān)。
CONCLUSION: Nimodipine relieves the neurodegeneration induced by aluminum overload through inhibiting the expression of HO-1 and keeping the homeostasis of iron.
結(jié)論：尼莫地平可能通過抑制HO-1表達(dá)、維持鐵離子穩(wěn)態(tài)，減輕鋁過負(fù)荷所致的神經(jīng)元退行性變。