Braf

常見例句

• Mutational activation of the BRAF oncogene is the most common genetic alteration in cutaneous melanoma.
  BRAF癌基因突變的激活是皮膚黑色素瘤最常見的基因改變。
• BRAF related molecules in MAPK signal transduction are potential treatment target of MM.
  BRAF突變相關(guān)的MAPK信號傳導(dǎo)分子是治療惡性黑素瘤的靶點。
• The BRAF mutation found in nevi and melanoma increases the activity of the BRAF protein, prompting cells to multiply abnormally.
  BRAF蛋白在調(diào)控生長以及分化的信號通路中有重要的作用。而這種突變使得BRAF蛋白的活性增強(qiáng)，進(jìn)而加速了異常的增殖。
• It's still controversial about the relationship of BRAF mutation with heredity, pre-existing pigment nevi, invasion and prognosis of MM.
  此突變與遺傳、預(yù)先存在的色素痣、腫瘤侵襲性及預(yù)后之間的關(guān)系還存在爭論。
• It is recognized now that RAS, ERK, especially BRAF kinase in the MAPK/ERK pathway probably play important roles in the development of MM.
  目前認(rèn)為,該信號轉(zhuǎn)導(dǎo)路徑中的RAS、ERK,尤其是BRAF激酶在黑素瘤的發(fā)生發(fā)展中可能有重要作用。
• But sometimes when the mutated BRAF gene is expressed in melanocytes, those cells go into a state of permanent hibernation via a process known as senescence.
  但是對于有些發(fā)生了BRAF基因突變的黑色素細(xì)胞來說，他們則會進(jìn)入持續(xù)的休眠期，即被稱為衰老。
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