Philadelphia chromosome
常見(jiàn)例句
- The Philadelphia chromosome (universally present in CML) is lacking in patients with leukemoid reactions.
費(fèi)城染色體(一般出現(xiàn)在CML)在白血病樣反應(yīng)中一般不出現(xiàn)。
www.goo--gle.com - Philadelphia chromosome formed may result in the generation of the fusion protein BCR ABL, a constitutively activated tyrosine ki nas e which then causes chronic myeloid leukemia (CML).
慢性粒細(xì)胞白血病(CML)患者體內(nèi)有異常染色體形成并產(chǎn)生BCR ABL融合蛋白,該融合蛋白能激活酪氨酸激酶,刺激細(xì)胞過(guò)度增生導(dǎo)致慢性粒細(xì)胞白血病的發(fā)生。 - The drug was originally developed as Imatinib using rational drug design after Philadelphia chromosome mutation was discovered.
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